Role of the Intestinal Epithelium and Its Interaction With the Microbiota in Food Allergy

Title: Role of the Intestinal Epithelium and Its Interaction With the Microbiota in Food Allergy
Creator: Ali, Ali; Tan, HuiYing; Kaiko, Gerard E.
Relation: NHMRC.APP1162666 & APP1146524 http://purl.org/au-research/grants/nhmrc/1146524
Relation: Frontiers in Immunology Vol. 11, Issue December 2020, no. 604054
Publisher Link: http://dx.doi.org/10.3389/fimmu.2020.604054
Publisher: Frontiers Research Foundation
Resource Type: journal article
Date: 2020
Description: The intestinal epithelial tract forms a dynamic lining of the digestive system consisting of a range of epithelial cell sub-types with diverse functions fulfilling specific niches. The intestinal epithelium is more than just a physical barrier regulating nutrient uptake, rather it plays a critical role in homeostasis through its intrinsic innate immune function, pivotal regulation of antigen sensitization, and a bi-directional interplay with the microbiota that evolves with age. In this review we will discuss these functions of the epithelium in the context of food allergy.
Subject: epithelium; microbiota, allergy; allergy, anaphyalaxis; anaphyalaxis; intestinal immunity
Identifier: http://hdl.handle.net/1959.13/1444597
Identifier: uon:42347
Identifier: ISSN:1664-3224
Language: eng
Reviewed